ايفوس 1 جم فيال

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جرعة دواءايفوس 1 جم فيال

يستعمل دواء ايفوس 1 جم فيالifos 1 gm vial(n/a) antineoplastic antineoplastic

about ifosfamide -alkylating agent (nitrogen mustard) antineoplastic - -mechanism of action of ifosfamide -in the liver drug undergo enzymatic activation into 4-hydroxyifosfamide.this alkylates the dna by binding to n7 position of the guanine residue. this results cross linking/abnormal base pairing/scission of dna strand. there is cross linking of nucleic acid with proteins can also takes place. the overall process is cell cycle nonspecific reaction. - -indications for ifosfamide -1. testicular cancer -2. breast cancer -3. non-hodgkins disease -4. hodgkins disease -5. soft tissue sarcoma -6. osteogenic sarcoma -7. lung cancer -8. cervical cancer -9. ovarian cancer -10. lymphocytic lymphoma -11. gastric cancer -12. pancreatic cancer -13. bladder cancer -14. cancer of endometrium -15. neuroblastoma -16. wilm`s tumor -

تركيبة دواءايفوس 1 جم فيالifos 1 gm vial(n/a)

يتركب هذا الدواء من :ifosfamide