فلورويوراسيل 250 مجم / 10 مل 5 امبول

ما هو دواء فلورويوراسيل 250 مجم / 10 مل 5 امبول

جرعة دواءفلورويوراسيل 250 مجم / 10 مل 5 امبول

يستعمل دواء فلورويوراسيل 250 مجم / 10 مل 5 امبولfluorouracil 250mg/10ml 5amps .i.v. antineoplastic antineoplastic

description -a pyrimidine analog that is an antineoplastic antimetabolite. it interferes with dna synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid - -mechanism of action the precise mechanism of action has not been fully determined but the main mechanism of fluorouracil is thought to be the binding of the deoxyribonucleotide of the drug (fdump) and the folate cofactor n5�10-methylenetetrahydrofolate to thymidylate synthase (ts) to form a covalently bound ternary complex. this results in the inhibition of the formation of thymidylate from uracil which leads to the inhibition of dna and rna synthesis and cell death. fluorouracil can also be incorporated into rna in place of uridine triphosphate (utp) producing a fraudulent rna and interfering with rna processing and protein synthesis.

تركيبة دواءفلورويوراسيل 250 مجم / 10 مل 5 امبولfluorouracil 250mg/10ml 5amps .i.v.

يتركب هذا الدواء من :fluorouracil