يوروميتكسان 400مجم/4مل 15 امبول

ما هو دواء يوروميتكسان 400مجم/4مل 15 امبول

جرعة دواءيوروميتكسان 400مجم/4مل 15 امبول

يستعمل دواء يوروميتكسان 400مجم/4مل 15 امبولuromitexan 400mg/4ml 15 i.v.amp. uroprotectant uroprotectant

about mesna -synthetic thiol derivative antidote uroprotectant. -mechanism of action of mesna -mesna rapidly oxidized to major metabolite mesna disulfide (dimesna). in the kidney dimesna reduced into free thiol compound. this compound reacts with the metabolites of oxazaphosphorins (cyclophosphamide or ifosfamide) to form stable nonurotoxic compounds. during this detoxification there is binding of mesna to the 4-hydroxy-ifosfamide forming a nonurotoxic 4-sulfoethylthioifosfamide.mesna also bind to the double bonds of acrolein and to other urotoxic metabolites. -indications for mesna -1. hemarragic cystitis secondary to cyclophosphamide or ifosamide -2. toxicity to the urinary passage caused by oxazaphosphorins such as ifosamide

تركيبة دواءيوروميتكسان 400مجم/4مل 15 امبولuromitexan 400mg/4ml 15 i.v.amp.

يتركب هذا الدواء من :mesna