سوميناليتا 15مجم/5مل 120مل

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جرعة دواءسوميناليتا 15مجم/5مل 120مل

يستعمل دواء سوميناليتا 15مجم/5مل 120ملsominaletta 15mg/5ml elixir 120 ml anti-epileptic.barbiturates anti-epileptic.barbiturates

about phenobarbitone -barbiturate derivative sedative-hypnotic anticonvulsant. -mechanism of action of phenobarbitone -sedative and antiepileptic actions: phenobarbitone mainly acts on picrotoxin site of gaba -bzd receptor cl- (chloride ion) channel complex. it prolongs the duration of gaba induced chloride channel opening and produces hyperpolarisation and decreases firing rate of neurons. this will alters the normal body functions. phenobarbitone also has gaba mimetic action. at high concentrations phenobarbitone directly increases chloride ion conductance and decreases transmission of calcium ion (ca2+ ) dependent neurotransmitters. phenobarbitone also inhibits excitatory glutamate neurotransmitters. at high concentration it also inhibits sodium ion channel and potassium ion channel. phenobarbitone is used as an antiepileptic to control partial and generalised tonic-clonic seizures. -barbiturates activate inhibitory gaba-a receptors and inhibit excitatory ampa receptors and produc

تركيبة دواءسوميناليتا 15مجم/5مل 120ملsominaletta 15mg/5ml elixir 120 ml

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