تاسيجنا 150مجم 28كبسول

ما هو دواء تاسيجنا 150مجم 28كبسول

جرعة دواءتاسيجنا 150مجم 28كبسول

يستعمل دواء تاسيجنا 150مجم 28كبسولtasigna 150 mg 28 caps. antineoplastic antineoplastic

indication for the potential treatment of various leukemias including chronic myeloid leukemia (cml). -pharmacodynamics nilotinib is a transduction inhibitor that targets bcr-abl c-kit and pdgf for the potential treatment of various leukemias including chronic myeloid leukemia (cml). -mechanism of action chronic myelogenous leukaemia (cml) is caused by the bcr-abl oncogene. nilotinib inhibits the tyrosine kinase activity of the bcr-abl protein. nilotinib fits into the atp-binding site of the bcr-abl protein with higher affinity than imatinib over-riding resistance caused by mutations. the ability of amn107 to inhibit tel-platelet-derived growth factor receptor-beta (tel-pdgfrbeta) which causes chronic myelomonocytic leukaemia and fip1-like-1-pdgfralpha which causes hypereosinophilic syndrome suggests potential use of amn107 for myeloproliferative diseases characterised by these kinase fusions (stover et al 2005; weisberg et al 2005). amn107 also inhibits the c-kit receptor k

تركيبة دواءتاسيجنا 150مجم 28كبسولtasigna 150 mg 28 caps.

يتركب هذا الدواء من :nilotinib