ارتامين 250 مجم 50 كبسولة

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يستعمل دواء ارتامين 250 مجم 50 كبسولةartamine 250mg 50caps. antirheumatic agent.wilson s disease.antidote chelating agent antirheumatic agent.wilson s disease.antidote chelating agent

indication for treatment of wilson s disease cystinuria and active rheumatoid arthritis. -mechanism of action penicillamine is a chelating agent recommended for the removal of excess copper in patients with wilson s disease. from in vitro studies which indicate that one atom of copper combines with two molecules of penicillamine. penicillamine also reduces excess cystine excretion in cystinuria. this is done at least in part by disulfide interchange between penicillamine and cystine resulting in formation of penicillamine-cysteine disulfide a substance that is much more soluble than cystine and is excreted readily. penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. the mechanism of action of penicillamine in rheumatoid arthritis is unknown although it appears to suppress disease activity. unlike cytotoxic immunosuppressants

تركيبة دواءارتامين 250 مجم 50 كبسولةartamine 250mg 50caps.

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