لونجيتينيب 150مجم 30قرص

ما هو دواء لونجيتينيب 150مجم 30قرص

جرعة دواءلونجيتينيب 150مجم 30قرص

يستعمل دواء لونجيتينيب 150مجم 30قرصlungitinib 150 mg 30 f.c. tabs. antineoplastic agent.epidermal growth factor receptor (egfr) inhibitor antineoplastic agent.epidermal growth factor receptor (egfr) inhibitor

pharmacology -reversibly inhibits overall epidermal growth factor receptor (her1/egfr) - tyrosine kinase activity. intracellular phosphorylation is inhibited which prevents further downstream signaling resulting in cell death. erlotinib has higher binding affinity for egfr exon 19 deletion or exon 21 l858r mutations than for the wild type receptor. - -indications -non-small cell lung cancer metastatic: treatment of metastatic non-small cell lung cancer (nsclc) in tumors with epidermal growth factor receptor (egfr) exon 19 deletions or exon 21 (l858r) substitution mutations as detected by an approved test either as first-line maintenance or as second or greater line treatment after progression following at least 1 prior chemotherapy regimen. -limitations of use: use in combination with platinum-based chemotherapy is not recommended. safety and efficacy of treatment for metastatic nsclc with egfr mutations other than exon 19 deletion or exon 21 (l858r) substitution have not been est

تركيبة دواءلونجيتينيب 150مجم 30قرصlungitinib 150 mg 30 f.c. tabs.

يتركب هذا الدواء من :erlotinib