تيرازين 5مجم 10 اقراص

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يستعمل دواء تيرازين 5مجم 10 اقراصterazin 5mg 10 tabs. alpha1 blocker alpha1 blocker

indication -for the treatment of symptomatic bph and mild to moderate hypertension. -mechanism of action in general a1-adrenergic receptors mediate contraction and hypertrophic growth of smooth muscle cells. a1-receptors are 7-transmembrane domain receptors coupled to g proteins gq/11. three a1-receptor subtypes which share approximately 75% homology in their transmembrane domains have been identified: a1a (chromosome 8) a1b (chromosome 5) and a1d (chromosome 20). terazosin is the first a1-receptor antagonist to demonstrate selectivity for the a1a-receptor. all three receptor subtypes appear to be involved in maintaining vascular tone. the a1a-receptor maintains basal vascular tone while the a1b-receptor mediates the vasocontrictory effects of exogenous a1-agonists. activation of a1-receptors activates gq-proteins which results in intracellular stimulation of phospholipases c a2 and

تركيبة دواءتيرازين 5مجم 10 اقراصterazin 5mg 10 tabs.

يتركب هذا الدواء من :terazosin