زابريتينز 1مجم 10 اقراص

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جرعة دواءزابريتينز 1مجم 10 اقراص

يستعمل دواء زابريتينز 1مجم 10 اقراصzapritens 1mg 10 f.c. tab. anti-hypertensive.ace anti-hypertensive.ace

description -one of the angiotensin-converting enzyme inhibitors (ace inhibitors) used for hypertension. it is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. - -indication -cilazapril is an ace inhibtor class drug used in the treatment of hypertension and heart failure. - -mechanism of action -cilazapril is a pyridazine ace inhibitor. it competes with angiotensin i for binding at the angiotensin-converting enzyme blocking the conversion of angiotensin i to angiotensin ii. as angiotensin ii is a vasoconstrictor and a negative feedback mediator for renin activity lower angiotensin ii levels results in a decrease in blood pressure an increase in renin activity and stimulation of baroreceptor reflex mechanisms. kininase ii an enzyme which degrades the vasodilator bradykinin is identical to ace and may also be inhibited.

تركيبة دواءزابريتينز 1مجم 10 اقراصzapritens 1mg 10 f.c. tab.

يتركب هذا الدواء من :cilazapril