اميبينيم / سيلاستاتين-كابي 500/500 مجم 10 فيال

ما هو دواء اميبينيم / سيلاستاتين-كابي 500/500 مجم 10 فيال

جرعة دواءاميبينيم / سيلاستاتين-كابي 500/500 مجم 10 فيال

يستعمل دواء اميبينيم / سيلاستاتين-كابي 500/500 مجم 10 فيالimipenem/cilastatin-kabi 500/500mg 10vials for i.v. inf. antibiotic antibiotic

about cilastatin -enzyme inhibitor antibiotic resistance reducer to imipenem -mechanism of action of cilastatin -cilastatin is an inhibitor of dehydropeptidase i an enzyme found in the brush border of the renal tubules. it is given as the sodium salt with imipenem to prevent its renal metabolism and protect against nephrotoxic effects -imipenem -description -semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria including many multiresistant strains. it is stable to beta-lactamases. -mechanism of action imipenem acts as an antimicrobial through the inhibition of cell wall synthesis of various gram-positive and gram-negative bacteria. this inhibition of cell wall synthesis in gram-negative bateria is attained by binding to pencillin binding proteins (pbps). in e. coli and selected strains of p. aeruginosa imipenem has shown to have the highest affinity to pbp-2 pbp-1a and pbp-1b.

تركيبة دواءاميبينيم / سيلاستاتين-كابي 500/500 مجم 10 فيالimipenem/cilastatin-kabi 500/500mg 10vials for i.v. inf.

يتركب هذا الدواء من :cilastatin+imipenem